Estimating the Division Rate of the Self-Similar Growth-Fragmentation Equation
نویسندگان
چکیده
We consider the growth-fragmentation equation and we address the problem of finding the division rate from the stable size distribution of the population, which is easily measured, but non-smooth. We propose a method based on the Mellin transform for growth-fragmentation equations with self-similar kernels. We build a sequence of functions which converges to the density of the population in division, simultaneously in several weighted L2 spaces, as the measurement error goes to 0. This improves previous results for self-similar kernels and allows us to understand the partial results for general fragmentation kernels. Numerical simulations confirm the theoretical results. Moreover, our numerical method is tested on real biological data, arising from a bacteria growth and fission experiment.
منابع مشابه
Estimating the division rate and kernel in the fragmentation equation
We consider the fragmentation equation ∂f ∂t (t, x) = −B(x)f(t, x) + ∫ y=∞ y=x k(y, x)B(y)f(t, y)dy, and address the question of estimating the fragmentation parameters i.e. the division rate B(x) and the fragmentation kernel k(y, x) from measurements of the size distribution f(t, ·) at various times. This is a natural question for any application where the sizes of the particles are measured e...
متن کاملEstimating the division rate for the growth-fragmentation equation.
Growth-fragmentation equations arise in many different contexts, ranging from cell division, protein polymerization, neurosciences etc. Direct observation of temporal dynamics being often difficult, it is of main interest to develop theoretical and numerical methods to recover reaction rates and parameters of the equation from indirect observation of the solution. Following the work done in Per...
متن کاملNonparametric Estimation of the Division Rate of a Size-Structured Population
We consider the problem of estimating the division rate of a size-structured population in a nonparametric setting. The size of the system evolves according to a transport-fragmentation equation: each individual grows with a given transport rate, and splits into two offsprings of the same size, following a binary fragmentation process with unknown division rate that depends on its size. In cont...
متن کاملA General Inverse Problem for the Growth-Fragmentation Equation
Aggregation-fragmentation equations arise in many different contexts, ranging from cell division, protein polymerization, biopolymers, neurosciences etc. Direct observation of temporal dynamics being often difficult, it is of main interest to develop theoretical and numerical methods to recover reaction rates and parameters of the equation from indirect observation of the solution. Following th...
متن کاملExponential decay for the growth-fragmentation/cell-division equation
We consider the linear growth-fragmentation equation arising in the modelling of cell division or polymerisation processes. For constant coefficients, we prove that the dynamics converges to the steady state with an exponential rate. The control on the initial data uses an elaborate Lnorm that seems to be necessary. It also reflects the main idea of the proof which is to use an anti-derivative ...
متن کامل